OK, I've got friends that are running 11:1 and 11.5:1 bottoms, ported heads, 10.5mm lift cams wigh HIGH duration cams, tuned and struggling to get 300-325. Doug Stewart is running the same cams on hogged heads, stock bottom, tuned with an real 292 RWHP. THe HP rating is Dyno specific I know. I just don't see how much more can be done, assuming the standard off the shelf stuff, headers, plenum, CAI, Tuner, cams, head work, higher compression. I've got over a grand sitting in a one off 78mm billet alimunim throttle body, that mated to hogged out Crawford plenum that made a whopping 11HP. People can keep trying to make stuff, but there is only so much chicken salad that can be made from Chicken manure, IMO.
I'm not saying that the VQ is a hunk of junk, on the contrary, it is a good motor, I am simply polling the difference of building a 'budget' VQ, Cosworth VQ, or swaping to a V8. Please ignore the HP targat I have set, just talking bang for the buck. I don't think the VQ will take boost, at least for long term.