Well a piggyback, yes. For a piggyback I would suggest emanage ultimate, BUT it's very limited since the f20 ECU absolutely can NOT be flashed. The piggybacks would be great for NA, but major mods like ITBs or stroking would really require a full ECU upgrade. Any FI more than seven or eight pounds would require a new one also.
I know this for a fact as I owned one for a couple years. 05 and under are SOL on flashing their ECUs. I'm not going to look for documentation to prove it, but you may notice on hondata's site that there is no hondata flash for 05 and under. "current only K20A, K20A2, K20A3, K24A2-TSX ECUs and 06 F22 S2000 ECUs can be re-flashed)"
A great site to do your f20c research on would be s2ki.com. Here's a link to "The official NA tuning/I want 230whp NA" thread: http://www.s2ki.com/forums/index.php?showtopic=336978&st=0
This thread has all your NA tuning needs as far as documentation goes.