Long time no see. I am back after a long time because I run MSQ 2 for 4 years now, so I can share some experiences.
After sitting on a shelf for 10 years I decided to install it in a Mazda B2200, sorry! Ripped out the carburetor and installed a Mopar TBI. My goal was fuel efficiency. My setup is MSQ2 Ver. 2.2 EFI only. I kept the original electronic ignition. I did some wiring changes on the V2.2 PCB before installing the EFI. How I did ignition timing:
1. installed the dizzy at 0 BTDC (there was a mark on the dizzy)
2. at idle rpm and timing light, adjusted the dizzy to 10 BTDC (vacuum advance disabled)
3. vacuum advance connected, at 2500 RPM ignition advance went to about 35 BTDC. Done
But that is for a Mazda 2.2L 4 cyl. engine. The EFI runs without any issues and my fuel efficiency increased to 28 MPG in mixed driving.