I've been doing some tuning of my Mikuni 44 set up as of late with the assistance of a wide band o2 sensor, and I have learned a few things that may be helpful to some others. Generally, I recommend determining these in the order listed:
Pilot Screws:
One bit from Honsowetz in the How to Modify Your Nissan Datsun OHC Engine which is a very specific instruction: run your pilot screws 1.5 turns out. I have mine set at 1.5 dead on, and the engine likes the 57.5 pilots at that setting. AFRs are where they should be for idle and low speed operation. The engine runs well in both of these