Cpt.,
Its not easy to get the NA EFI to work properly in a turbo application. Obviously, I'm making an assumption that that is your intentions. If you're asking from a mechanical pespective, yes it can be done that way. Depending on who you ask, it may be less than 'ideal', however. A modest motor, using premium fuel and an appropriate intercooler would probably be an overall improvement as the higher compression (relative to a stock ZXT) would reduce lag a bit. The higher ring lands are a step backward, but if the car is used for sprints (as opposed to extended use), I suspect you'd be fine.
You'd be wise getting your hands on a 280ZXT EFI system, providing your goal is modest power. If your ultimate or long-term goals include high power levels, I'd recommend an aftermarket EFI system.