Wouldn't you want to keep the A/F mixture coming into the engine closer to the flame front? With the first set of pistons, you'll be sending all the mixture to the outside, closer to the ring lands, away from the flame front. Since the ringland is what's weakest on the pistons, I would choose the second set to keep the A/F in the center close to the flame front. Closer to the flame front, less timing you need to make power also.