Lack of power steering can pose a problem for some people. Without aftermarket adjustment, you can't dial in a whole lot of caster on an S30, which affects the spinback rate of the steering wheel. Since plenty of caster is important especially in short wheelbase cars, the driver has to manually spin the wheel back. Some people can handle it, some people cant. More of a personal preference than anything.
As far as the mcpherson struts, the lack of upper control arms in the rear pose the problem. While this too, can be addressed by the driver, it's not optimal. The lack of upper control arms means there's only two pivot points in the rear suspension, where the top of the shock bolts to the shock tower and where the lower control arm bolts to the subframe. Whereas in a situation with upper control arms, like a 240sx or Miata, there are more pivoting points.
The point being, whenever the shock becomes compressed, when in a situation of hard cornering, negative camber is actually increased, which decreases the contact patch. However, with enough speed/roll, the contact patch can be compensated for.
Bottom line is, any handicaps on a car can be compensated for with driver skill. However, you can't overlook the fact that some chassis aren't as optimal for drifting as others.