Having a 3 car garge similar to the setup in the pics, but mine is in the back of the house on an alley, I would go w/ the way it sits. If you ever want to pull something big into the garage you will be very happy that you have 22' to manage through then 10'.
Don't care what it looks like. Try and navigate a 101" trailer through a 10' door, not fun.
Too bad the roof line is the way it is. One thing I did was swap the 20' door w/ the location of the 10' door. Let my wife have closer access to the garage door for less worries on me.