Depends on how you define throttle response. If you want your engine to have on and off throttle response, like a pushbutton instead of a pedal, then I suppose the largest throttle body you can find works. However, I prefer a gradual climb in airflow that is a lot more proportional to throttle valve angle.
Any engine of X size is going to have a flow ceiling in the throttle body (TB) area. The bigger TB you have, the higher the ceiling for the throttle body. OEMs more or less match the throttle body to the engine size. If you increase the TB size and keep the same engine, all you do is increase the ceiling, whether or not the engine can actually reach it. But since your engine still flows the same as it did before, you get to the engine's max flow at whatever RPM, at lower throttle valve angles. Perhaps there's a marginal increase in flow overall due to the plate being less of a restriction compared to overall throttle body area, but it's not worth it unless you are really shoving lots of air in the motor.