Stock Ljet can meet that goal.
I didn't have a specific brand in mind, but Megasquirt will do.
Yes, batch-fired.
Yes, Sequential.
I get the idea that two things are attracting you to the Mopar... Closed loop and Sequential injection.
Sequential injection will only help incrementally. Its not the end-all be-all in EFI. Don't put all your eggs in that basket. For example, there is a member here with a 280zxt, running 7.4:1 CR (not exactly ideal for MPG), getting 30 MPG (hwy) with a sequential (aftermarket) system. Here's the kicker... he's never timed his injectors to the valve events. He has no idea how far off the events may be. So, did he get lucky, or is it just not that significant?
Closed loop is the mixture trimming I believe you are referring to. Keeping it simple... this is only happening under cruise conditions and the target is 14.7:1 AFR. While 14.7 is the best compromise for emission's, it is not normally where peak MPG is going to be found. Leaner, much leaner in some cases, will usually net better MPG. One could say... the idea you're holding on to, is actually working against your goals.
Disclaimer: I've made some assumptions about the Mopar EFI based on what you've given us. If your information is wrong, then so is mine.