The fuel pressure is the same from the FPR, all the way back through the lines to the pump. If you want to get REAL technical, there will be a SLIGHT drop each time an injector opens, but the FPR will recover quickly. By all rights you could place the FPR back at the tank, and not notice any changes in fuel pressure at the rail that are out of the ordinary, would just be a pointless endevour though.
I have my Aeromotive AFPR located where the original fuel pump was and have not had an issue.
The hose from the end of the fuel rail travels under the upper rad hose and to the FPR, so maybe a slight be shorter than yours that goes over the cam cover, but similar idea.