I'm running a Haltech E11 v2 with 6 LS1 coil packs and 550cc injectors in full sequential. Using the 300zx trigger wheel and the original dizzy for crank and cam timing made everything real easy to set up (no fabrication). The tuning is easy with this EMS, it doesn't even sound like a L28 anymore because it idles so smooth. Just make sure whoever tunes your car that they specialize in that EMS, it will save you money tunnig on a Dyno if they already know there way around the software.
As said in a previous post, it does make sense that running sequential is allot less taxing on the ignition and fuel components. Not to mention you wont be flushing precious gas down the drain.